| Bioactivity | MS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice[1]. |
| Target | EC50: 53 nM (TSHR) |
| Name | MS438 |
| CAS | 512840-45-8 |
| Formula | C20H17F3N2O3 |
| Molar Mass | 390.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Latif R, et al. New small molecule agonists to the thyrotropin receptor. Thyroid. 2015 Jan;25(1):51-62. |