| Bioactivity | Lynronne-1 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 8-32 μg/mL for methicillin-resistant MRSA strains). Lynronne-1 reduces the bacterial load in MRSA infected wound murine model. Lynronne-1 is also effective against P. aeruginosa infection[1]. |
| Name | Lynronne-1 |
| Sequence | Leu-Pro-Arg-Arg-Asn-Arg-Trp-Ser-Lys-Ile-Trp-Lys-Lys-Val-Val-Thr-Val-Phe-Ser-NH2 |
| Shortening | LPRRNRWSKIWKKVVTVFS-NH2 |
| Formula | C113H183N35O23 |
| Molar Mass | 2399.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Oyama LB, et al. The rumen microbiome: an underexplored resource for novel antimicrobial discovery. NPJ Biofilms Microbiomes. 2017 Dec 1;3:33. [2]. Mulkern AJ, et al. Microbiome-derived antimicrobial peptides offer therapeutic solutions for the treatment of Pseudomonas aeruginosa infections. NPJ Biofilms Microbiomes. 2022 Aug 29;8(1):70. |