Bioactivity | MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM),involved in osteoarthritis (OA)[1]. |
Target | IC50: 91 μM (MMP-1), 99 μM (MMP-2), 68 μM (MMP-9), 14.6 μM (MMP-13), 63 μM (MMP-14) |
Name | MMP13-IN-4 |
CAS | 514855-02-8 |
Formula | C21H17BrN4O5 |
Molar Mass | 485.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Cuffaro D, et al. Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization. Int J Mol Sci. 2023 Jul 4;24(13):11098. |