| Bioactivity | MLS000389544 is a selective and potent methylsulfonylnitrobenzoate thyroid hormone receptor β (TRβ) antagonist that blocks the association of TRβ with steroid receptor coactivator 2 (SRC2)[1][2]. |
| CAS | 573965-48-7 |
| Formula | C20H24N2O7S |
| Molar Mass | 436.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mire Zloh, et al. Evidence that diclofenac and celecoxib are thyroid hormone receptor beta antagonists. Life Sci. 2016 Feb 1:146:66-72. [2]. "Ronald L Johnson, et al. A Quantitative High-hroughput Screen Identifies ovel Inhibitors of the Interaction of hyroid eceptor β with a Peptide of Steroid eceptor oactivator 2. J Biomol Screen. 2011 Jul;16(6):618-27." |
MLS000389544
CAS: 573965-48-7 F: C20H24N2O7S W: 436.48
MLS000389544 is a selective and potent methylsulfonylnitrobenzoate thyroid hormone receptor β (TRβ) antagonist that bl
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