| Bioactivity | ML179 (SR-1309) is a inverse LRH1 (Liver receptor homologue-1) agonist with IC50 of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer[1]. | ||||||||||||
| Target | LRH-1 | ||||||||||||
| Name | ML179 | ||||||||||||
| CAS | 1883548-87-5 | ||||||||||||
| Formula | C21H25F3N4O2 | ||||||||||||
| Molar Mass | 422.44 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Busby S, et al. Discovery of Inverse Agonists for the Liver Receptor Homologue-1 (LRH1; NR5A2). 2010 Oct 12 [updated 2011 Dec 12]. |