ML-030_product_DataBase

CAS: 1013750-77-0 F: C20H20N4O4S W: 412.46

ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1,

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2, respectively.

Target

IC50: 6.7 nM (PDE4A), 12.9 nM (PDE4A1), 48.2 nM (PDE4B1), 37.2 (PDE4B2) nM, 452 (PDE4C1) nM, 49.2 (PDE4D2) nM

Invitro

ML-030 is potent in cell-based assay with an EC50 value of 18.7 nM[1].

Name

ML-030

CAS

1013750-77-0

Formula

C20H20N4O4S

Molar Mass

412.46

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Skoumbourdis AP, et al. Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3686-92.

PeptideDB

ML-030

CAS: 1013750-77-0 F: C20H20N4O4S W: 412.46