| Bioactivity | MK-8457 is a dual SYK/ZAP70 inhibitor. MK-8457 can be used for research of rheumatoid arthritis[1]. |
| CAS | 1312518-84-5 |
| Formula | C24H25F3N4O3S |
| Molar Mass | 506.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Coffey G, et al. PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers. J Clin Pharmacol. 2017 Feb;57(2):194-210. |