PeptideDB

MK-1084

CAS: 2641216-67-1 F: C32H31ClF2N6O4 W: 637.08

MK-1084 is a selectiveKRAS G12Cinhibitor that is currently in Phase I clinical trial (NCT05067283). MK-1084 exhibits ant
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity MK-1084 is a selective KRAS G12C inhibitor that is currently in Phase I clinical trial (NCT05067283). MK-1084 exhibits anticancer activity and can be used either alone or in combination with pembrolizumab (HY-P9902) for cancer research[1].
CAS 2641216-67-1
Formula C32H31ClF2N6O4
Molar Mass 637.08
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Rojas C, et al. 663P Safety and preliminary efficacy of the KRAS G12C inhibitor MK-1084 in solid tumors and in combination with pembrolizumab in NSCLC[J]. Annals of Oncology, 2023, 34: S466-S467.