| Bioactivity | MIR96-IN-1 targets the Drosha site in the miR-96 (miRNA-96, microRNA-96) hairpin precursor, inhibiting its biogenesis, derepressing downstream targets, and triggering apoptosis in breast cancer cells. MIR96-IN-1 binds to RNAs with Kds of 1.3, 9.4, 3.4, 1.3 and 7.4 μM for RNA1, RNA2, RNA3, RNA4 and RNA5, respectively[1]. | ||||||||||||
| Invitro | MIR96-IN-1 (Compound 1) selectively inhibits production of mature miR-96 and triggers apoptosis in breast cancer cells at micromolar concentrations[1].MIR96-IN-1 (Compound 3) binds a UU loop in miR-96 and inhibits its biogenesis[2]. | ||||||||||||
| Name | MIR96-IN-1 | ||||||||||||
| CAS | 1311982-88-3 | ||||||||||||
| Formula | C33H48N8O2 | ||||||||||||
| Molar Mass | 588.79 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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MIR96-IN-1
CAS: 1311982-88-3 F: C33H48N8O2 W: 588.79
MIR96-IN-1 targets the Drosha site in the miR-96 (miRNA-96, microRNA-96) hairpin precursor, inhibiting its biogenesis, d
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