| Bioactivity | METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1]. |
| Invitro | METTL3-IN-2 inhibits METTL3 activity with an IC50 value of 6.1 nM[1].METTL3-IN-2 (0-30 μM; 120 h) inhibits cell proliferation of Caov3 cells[1].METTL3-IN-2 (0-30 μM; 120 h) inhibits growth of KASUMI cells with an IC50 value of 315.8 nM[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | METTL3-IN-2 |
| CAS | 2767258-88-6 |
| Formula | C25H26N8O |
| Molar Mass | 454.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hardick, DJ, et al. Preparation of heteroaromatic compounds as METTL3 inhibitory compounds. WO2022074379. 2022. |
METTL3-IN-2
CAS: 2767258-88-6 F: C25H26N8O W: 454.53
METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of
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