Bioactivity | Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively[1][2]. |
Target | Viral DNA polymerase |
Name | Cidofovir diphosphate |
CAS | 142276-31-1 |
Formula | C8H16N3O12P3 |
Molar Mass | 439.15 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hitchcock MJM, et al. Cidofovir, a New Agent with Potent Anti-Herpesvirus Activity. 1996. [2]. Magee WC, et al. Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Antimicrob Agents Chemother. 2005 Aug;49(8):3153-62. |