| Bioactivity | MEISi-1 is a homeodomain inhibitor of small molecule MEIS1 protein. MEISi-1 significantly inhibited the activity of luciferase reporter genes containing MEIS binding sites (TGACAG) and induced self-renewal of mouse and human HSCS in vitro and in vivo. MEISi-1 can be used for research in blood diseases, heart regeneration and cancer[1]. |
| CAS | 446306-43-0 |
| Formula | C24H24N2O3 |
| Molar Mass | 388.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Turan R D, et al. Development of Small Molecule MEIS Inhibitors that modulate HSC activity[J]. Scientific reports, 2020, 10(1): 7994. |