Bioactivity | (Rac)-Tipifarnib ((Rac)-IND 58359; (Rac)-R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac)-Tipifarnib showed significant in vivo antitumor effects after oral administration to mice[1]. |
CAS | 192185-68-5 |
Formula | C27H22Cl2N4O |
Molar Mass | 489.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Venet M, et al. Farnesyl protein transferase inhibitor ZARNESTRA™ R115777-History of a discovery[J]. Current Topics in Medicinal Chemistry, 2003, 3(10): 1095-1102. |