Bioactivity | MBL-IN-2 ((2R, 2R')-5αC) is an inhibitor of Metallo-β-lactamase (MBL) that can inhibit New Delhi Metallo-β-lactamase-1 (NDM-1) with an IC50 of 0.3 μM. MBL-IN-2 ((2R, 2R')-5αC) can be used for the study of resistance to β-lactam antibiotics[1]. |
Target | IC50:0.3 μM (NDM-1). |
Name | MBL-IN-2 |
Formula | C9H12F3NO3S |
Molar Mass | 271.26 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kondratieva A, et al. Fluorinated captopril analogues inhibit metallo-β-lactamases and facilitate structure determination of NDM-1 binding pose[J]. European Journal of Medicinal Chemistry, 2024: 116140. |