| Bioactivity | MART-1 nonamer antigen (LAGIGILTV) is a melanoma antigen that can be recognized by T cells. MART-1 nonamer antigen behaves as a superagonist by in vitro inducing specific T cells with enhanced immunological functions. MART-1 nonamer antigen can be used as a model to design peptides for use in anti-tumour vaccines[1]. |
| CAS | 204060-43-5 |
| Sequence | Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val |
| Shortening | LAGIGILTV |
| Formula | C40H73N9O11 |
| Molar Mass | 856.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rivoltini L, et al. A superagonist variant of peptide MART1/Melan A27-35 elicits anti-melanoma CD8+ T cells with enhanced functional characteristics: implication for more effective immunotherapy. Cancer Res. 1999 Jan 15;59(2):301-6. |
MART-1 nonamer antigen
CAS: 204060-43-5 F: C40H73N9O11 W: 856.06
MART-1 nonamer antigen (LAGIGILTV) is a melanoma antigen that can be recognized by T cells. MART-1 nonamer antigen behav
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