| Bioactivity | MAPK4 inhibitor 3 (compound 23b) is an inhibitor of MAPK4 with an IC50 value of 1.01 μM. MAPK4 inhibitor 3 inhibits cancer cells growth. MAPK4 inhibitor 3 can be used for research on cancer and tauopathies[1]. |
| Target | Microtubule affinity-regulating kinase 4 (MARK4)IC50:1.01 μM (Microtubule affinity-regulating kinase 4, MARK4) |
| Invitro | MAPK4 inhibitor 3 (1-20 μM， 24 h) 抑制 Hela 和 U87MG 生长，EC50 值分别为 2.52 μM 和 4.22 μM[1]。 Cell Viability Assay[1] Cell Line: |
| Name | MARK4 inhibitor 3 |
| Formula | C33H27FN4O3 |
| Molar Mass | 546.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Maria Voura, et al. Synthesis, Structural Modification, and Bioactivity Evaluation of Substituted Acridones as Potent Microtubule Affinity-Regulating Kinase 4 Inhibitors. ACS Pharmacology & Translational Science 2023 6 (7), 1052-1074. |
MARK4 inhibitor 3
CAS: F: C33H27FN4O3 W: 546.59
MAPK4 inhibitor 3 (compound 23b) is an inhibitor of MAPK4 with an IC50 value of 1.01 μM. MAPK4 inhibitor 3 inhibits can
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