| Bioactivity | MAO-B-IN-19 is a selective MAO-B inhibitor with an IC50 of 0.67 μM. MAO-B-IN-19 shows neuroprotective and anti-inflammatory properties[1]. |
| Invitro | MAO-B-IN-19（化合物 3f）显着抑制自身诱导的 Aβ1-42 聚集，并对 Aβ25-35 诱导的 PC12 细胞损伤显示出显着的神经保护作用。MAO-B-IN-19 是一种选择性金属螯合剂，可以抑制 Cu2+ 诱导的 Aβ1-42 聚集[1]。 |
| Name | MAO-B-IN-19 |
| CAS | 152897-41-1 |
| Formula | C15H11FO2 |
| Molar Mass | 242.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rui Chen, et al. Development of the "hidden" multi-target-directed ligands by AChE/BuChE for the treatment of Alzheimer's disease. Eur J Med Chem. 2023 May 5;251:115253. |