| Bioactivity | MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1]. |
| Invitro | MALT1-IN-11 (Example 151, 24 h) 抑制 OCI-LY10 细胞中 IL10 的分泌[1]。 |
| Name | MALT1-IN-11 |
| CAS | 2812352-99-9 |
| Formula | C20H16F4N8O |
| Molar Mass | 460.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shulu FENG, et al. Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disoders. Patent. WO2022164789. |
MALT1-IN-11
CAS: 2812352-99-9 F: C20H16F4N8O W: 460.39
MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 se
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