| Bioactivity | MAC13772 is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound[1]. | ||||||||||||
| Target | IC50: 250 nM (BioA) | ||||||||||||
| Name | MAC13772 | ||||||||||||
| CAS | 4871-40-3 | ||||||||||||
| Formula | C8H9N3O3S | ||||||||||||
| Molar Mass | 227.24 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Zlitni S, et al. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9(12):796-804. |