| Bioactivity | Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1]. | ||||||||||||
| Invitro | The estimate of the apparent terminal half-life of Ferroquine is 15.9 days. However, the equally active principal metabolite Desmethyl ferroquine (DMFQ) has a longer t1/2z, with an overall mean estimate of 31.4 days[1]. | ||||||||||||
| Name | Desmethyl ferroquine | ||||||||||||
| CAS | 903546-18-9 | ||||||||||||
| Formula | C22H22ClFeN3 | ||||||||||||
| Molar Mass | 419.73 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73. |
Desmethyl ferroquine
CAS: 903546-18-9 F: C22H22ClFeN3 W: 419.73
Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmeth
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