Lyso Flipper-TR 29_product_DataBase

Bioactivity	Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form[1].
Invitro	Lyso Flipper-TR 29 通过瞬时去质子化进入溶酶体，以中性形式穿过疏水膜扩散，但它不可能返回胞质溶胶，因为溶酶体内的低 pH 值约 5，会阻止瞬时去质子化。Lyso Flipper-TR 29 还跟踪晚期内体，但无法标记早期内体 (EE)，因为其内部 pH 太高，大于 6，无法防止瞬时去质子化[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Lyso Flipper-TR 29 相关抗体:
CAS	2324152-35-2
Formula	C35H37N5O4S6
Molar Mass	784.09
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Xiao-Xiao Chen, et al. Fluorescent Flippers: Small-Molecule Probes to Image Membrane Tension in Living Systems. Angew Chem Int Ed Engl. 2023 May 8;62(20):e202217868.

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