| Bioactivity | Luzopeptin A (BBM-928 A) is an actinoleukin-like antitumor antibiotic. Luzopeptin A is a bifunctional DNA intercalator which can interact with isolated DNA molecules. Luzopeptin A induces an unwinding-rewinding process of the closed superhelical PM2 DNA. Luzopeptin A is active against HIV-1 and HIV-2 reverse transcriptase with IC50s of 7 nM and 68 nM for HIV-1 RT and HIV-2 RT, respectively[1][2]. |
| CAS | 75580-37-9 |
| Formula | C64H78N14O24 |
| Molar Mass | 1427.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Konishi M, Ohkuma H, Sakai F, et al. Structures of BBM-928 A, B, and C. Novel antitumor antibiotics from Actinomadura luzonensis[J]. Journal of the American Chemical Society, 1981, 103(5): 1241-1243. |
Luzopeptin A
CAS: 75580-37-9 F: C64H78N14O24 W: 1427.38
Luzopeptin A (BBM-928 A) is an actinoleukin-like antitumor antibiotic. Luzopeptin A is a bifunctional DNA intercalator w
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