| Bioactivity | LpxC-IN-15 ((S)-13j) is a potent LpxC inhibitor with Ki values of 9.05, 5.6 nM for EcLpxC C63A, PaLpxC, respectively. LpxC-IN-15 shows antibacterial activity[1]. |
| Target | Ki: 9.05 nM (EcLpxC C63A); 5.6 nM (PaLpxC) |
| Formula | C32H32N4O5 |
| Molar Mass | 552.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mielniczuk S, et al. Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity. J Med Chem. 2024 Oct 10;67(19):17363-17391. |