Bioactivity | Longestin is a specific inhibitor of phosphodiesterase with antitrypanosomal activity, which is derived from Streptomyces argenteolus. Longestin is promising for research of anti-amnesia agent[1][2]. |
CAS | 131774-53-3 |
Formula | C61H88O17 |
Molar Mass | 1093.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ozaki T, et al. Enzymatic Formation of a Skipped Methyl-Substituted Octaprenyl Side Chain of Longestin (KS-505a): Involvement of Homo-IPP as a Common Extender Unit. Angew Chem Int Ed Engl. 2018 May 28;57(22):6629-6632. [2]. Hayashi Y, et al. Cloning of the gene cluster responsible for biosynthesis of KS-505a (longestin), a unique tetraterpenoid. Biosci Biotechnol Biochem. 2007 Dec;71(12):3072-81. |