| Bioactivity | BIIB 513 is an inhibitor of NHE 1 that protects against myocardial ischemia. BIIB 513 inhibits acid load recovery with an IC50 of 27 nmol/L in cells expressing wild-type NHE 1 under acute acid load[1]. |
| CAS | 265986-98-9 |
| Formula | C19H25N5O8S2 |
| Molar Mass | 515.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gumina, et al. "Inhibition of the Na+/H+ exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs." Circulation 100.25 (1999): 2519-2526. |
BIIB 513
CAS: 265986-98-9 F: C19H25N5O8S2 W: 515.56
BIIB 513 is an inhibitor of NHE 1 that protects against myocardial ischemia. BIIB 513 inhibits acid load recovery with a
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