| Bioactivity | Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. |
| Invitro | Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium promotes growth, induces differentiation and regualtes metabolic effects[2]. |
| Name | Liothyronine sodium |
| CAS | 55-06-1 |
| Formula | C15H11I3NNaO4 |
| Molar Mass | 672.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |