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Levomefolic acid-13C,d3

CAS: 1356019-94-7 F: C1913CH22D3N7O6 W: 463.47

Levomefolic acid-13C,d3is the deuterium labeledLevomefolic acid(HY-14781). Levomefolic acid (5-MTHF) is an orally active
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Bioactivity Levomefolic acid-13C,d3is the deuterium labeledLevomefolic acid(HY-14781)[1]. Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
Name Levomefolic acid-13C,d3
CAS 1356019-94-7
Formula C1913CH22D3N7O6
Molar Mass 463.47
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.