Leucosceptoside A_product_DataBase

Bioactivity	Leucosceptoside A is a phenylethanoid glycoside with anti-hyperglycemic and anti-hypertensive activities. Leucosceptoside A shows inhibitory activity against α-glucosidase and PKCα (IC50 of 19.0 μM)[1][2][3].
Invitro	Leucosceptoside A shows weak angiotensin converting enzyme (ACE) inhibitory effect[1].Leucosceptoside A (4-16 μM) significantly reduces 1-methyl-4-phenylpyridinium ion (MPP+)-induced death of mesencephalic neurons[2].
Name	Leucosceptoside A
CAS	83529-62-8
Formula	C30H38O15
Molar Mass	638.61
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Chika Ifeanyi Chukwuma, et al. Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review. J Ethnopharmacol. 2019 May 10;235:329-360. [2]. Yan-Yun Li, et al. Pedicularioside A from Buddleia lindleyana inhibits cell death induced by 1-methyl-4-phenylpyridinium ions (MPP+) in primary cultures of rat mesencephalic neurons. Eur J Pharmacol. 2008 Jan 28;579(1-3):134-40. [3]. B N Zhou, et al. Phenylethanoid glycosides from Digitalis purpurea and Penstemon linarioides with PKCalpha-inhibitory activity. J Nat Prod. 1998 Nov;61(11):1410-2.

PeptideDB