| Bioactivity | 11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively[1]. |
| Name | 11β-HSD1-IN-6 |
| CAS | 1303515-33-4 |
| Formula | C21H19ClN4O |
| Molar Mass | 378.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bo Qu, et al. Large-Scale Enantioselective Reduction of 2,3-Disubstituted Indenopyridine Enables a Practical Manufacturing Process for an 11β-HSD-1 Inhibitor. Org. Process Res. Dev. 2022, 26(3):963–975. |
11β-HSD1-IN-6
CAS: 1303515-33-4 F: C21H19ClN4O W: 378.85
11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the inter
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