| Bioactivity | Lenalidomide-F is a E3 ligase ligand for LWY713. LWY713 is a PROTAC-class FLT3 degrader (DC50 = 0.64 nM), which selectively induces FLT3 degradation via cereblon and proteasome-dependent pathways[1]. | ||||||
| CAS | 2359705-88-5 | ||||||
| Formula | C13H11FN2O3 | ||||||
| Molar Mass | 262.24 | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Store at room temperature 3 years
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| Reference | [1]. Liu W et al. Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia. Eur J Med Chem. 2023 Nov 19;264:115974. |
Lenalidomide-F
CAS: 2359705-88-5 F: C13H11FN2O3 W: 262.24
Lenalidomide-F is a E3 ligase ligand for LWY713. LWY713 is a PROTAC-class FLT3 degrader (DC50 = 0.64 nM), which selectiv
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