Bioactivity | LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 [1]. |
Name | LUT014 |
CAS | 2274819-46-2 |
Formula | C27H19F3N8O |
Molar Mass | 528.49 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Noa Shelach. Novel braf inhibitors and use there of for treatment of cutaneous reactions. WO2019026065A2. |