| Bioactivity | LTB4 antagonist 2, a carboxamide-acid compound, is an antagonist of leukotriene B4 (LTB4) with potentially anti-inflammatory activity. LTB4 antagonist 2 shows good affinity for the LTB4 receptor with IC50 of 439 nM[1]. |
| Invitro | LTB4 antagonist 2 (compound 24c) (0.1 μM，10 μM) 显示特异性结合 LTB4 的抑制作用，在 0.1 μM 和 10 μM 时分别具有 25% 和 95% 的抑制率[1]。 |
| Name | LTB4 antagonist 2 |
| Formula | C26H23NO6 |
| Molar Mass | 445.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bouissane L, et al. New and promising type of leukotriene B4 (LTB4) antagonists based on the 1,4-benzodioxine structure. Eur J Med Chem. 2023 Jun 5;254:115332. |