Bioactivity | LTA4H-IN-2 (compound (S)-2 ) is an orally active inhibitor of Leukotriene A4 Hydrolase, with an IC50 of <3 nM[1]. |
Target | IC50: <3 nM (Leukotriene A4 Hydrolase). |
Name | LTA4H-IN-2 |
CAS | 2851480-52-7 |
Formula | C20H19FN6O2 |
Molar Mass | 394.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gebhard Thoma, et al. Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. J Med Chem. 2023 Dec 14;66(23):16410-16425. |