| Bioactivity | LSN3353871 is a potent inhibitor of lipoprotein(a) (Lp(a)) that can binds to Kringle IV (KIV) 8, KIV7–8 and KIV5–8, with Kd of 756 nM, 605 nM and 423 nM, respectively. LSN3353871 disrupts the formation of Lp(a) with the IC50 of 1.69 µM. LSN3353871 has oral bioactivity[1]. |
| CAS | 2565657-20-5 |
| Formula | C13H18ClNO2 |
| Molar Mass | 255.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nuria Diaz, et al. Discovery of potent small-molecule inhibitors of lipoprotein(a) formation. Nature. 2024 May;629(8013):945-950. |
LSN3353871
CAS: 2565657-20-5 F: C13H18ClNO2 W: 255.74
LSN3353871 is a potent inhibitor of lipoprotein(a) (Lp(a)) that can binds toKringle IV (KIV) 8, KIV7–8 and KIV5–8, wit
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