| Bioactivity | LL-Z1640-4 is a potent p38/JNK signaling inhibitor. LL-Z1640-4 significantly diminishes p38 and JNK activation in HCC cells transfected with MLK4 siRNA. LL-Z1640-4 markedly attenuates ROS production induced by MLK4 knockdown. LL-Z1640-4 significantly reduces the apoptotic cells in HCC cells transfected with siMLK4[1][2]. |
| Invitro | LL-Z1640-4 markedly restores the number of cells in migration and invasion decreased by siMLK4, and significantly up-regulates expression of MMP2 and Vimentin[2]. |
| Name | LL-Z1640-4 |
| CAS | 66018-41-5 |
| Formula | C19H24O7 |
| Molar Mass | 364.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |