| Bioactivity | LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1]. |
| In Vivo | LJP 1586（0-10mg/kg，口服）可完全抑制大鼠肺 SSAO，ED50 介于 0.1 至 1 mg/kg 之间，药效半衰期大于 24 小时[1]。 |
| Name | LJP 1586 |
| CAS | 955037-42-0 |
| Formula | C11H15ClFNO |
| Molar Mass | 231.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. O'Rourke AM, et al. Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity. J Pharmacol Exp Ther. 2008 Feb;324(2):867-75. |
LJP 1586
CAS: 955037-42-0 F: C11H15ClFNO W: 231.69
LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally act
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