Bioactivity | LIN28-IN-2 (Compound Ln268) blocks the binding of the zinc finger domain (ZKD) of Lin28 to RNA substrates, and inhibits Lin28a and Lin28b. LIN28-IN-2 inhibits the proliferation of Lin28-positive cancer cell and spheroid growth[1]. |
Formula | C9H7FN2O2S |
Molar Mass | 226.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Matias-Barrios VM, et al., Developing novel Lin28 inhibitors by computer aided drug design. Cell Death Discov. 2025 Jan 12;11(1):5. |