| Bioactivity | LEI-800 is a DNA gyrase inhibitor with the IC50 of 35 nM. LEI-800 is potent antibacterial with the MIC values of 3.1 and 6.25 μM aganist E. coli and K. pneumoniae, resdpectively[1]. |
| CAS | 3040218-10-5 |
| Formula | C25H24N4O2S |
| Molar Mass | 444.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bakker AT, et al. Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nat Chem. Published online June 19, 2024. |