| Bioactivity | LC3in-C42 is a cell-active LC3A/B and autophagy covalent inhibitor. LC3in-C42 selectively inhibits the binding of P62 to LC3A/B in vitro and at the cellular level like D5 and can function on a lower concentration[1]. |
| Invitro | LC3in-C42是通过优势片段的杂交发现的，其效力 (IC50 = 7.6 nM) 与DC-LC3inD5相比有了很大的提高[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> LC3in-C42 相关抗体: |
| Formula | C19H21Cl2N3O2 |
| Molar Mass | 394.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhenfei Zhou, et al. Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor. J Med Chem. 2024 Jul 25;67(14):12184-12204. |