| Bioactivity | LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research[1]. | ||||||||||||
| Invitro | LASV inhibitor 3.3 (1 nM-100 μM；1 h) 抑制指示病毒糖蛋白假型的鼠白血病病毒 (MLV) 转导，IC50 值为 1.8 μM[1]。LASV inhibitor 3.3 (1 和 10 μM；1 h) 抑制 LAMP1 与 LASV GP 的结合[1]。 Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | LASV inhibitor 3.3 | ||||||||||||
| CAS | 554438-52-7 | ||||||||||||
| Formula | C30H37N3O2 | ||||||||||||
| Molar Mass | 471.63 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Wang MK, et al. Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1. PLoS Pathog. 2018 Sep 28;14(9):e1007322. |
LASV inhibitor 3.3
CAS: 554438-52-7 F: C30H37N3O2 W: 471.63
LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and pro
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