Bioactivity | L-Methionine-DL-sulfoximine (MSX) is an inhibitor of glutamine synthetase. L-Methionine-DL-sulfoximine is also a potent convulsant which metabolically and morphologically primarily affects astroglia. | ||||||||||||
Name | L-Methionine-DL-sulfoximine | ||||||||||||
CAS | 15985-39-4 | ||||||||||||
Formula | C5H12N2O3S | ||||||||||||
Molar Mass | 180.23 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Albrecht J, Norenberg MD. L-methionine-DL-sulfoximine induces massive efflux of glutamine from cortical astrocytes in primary culture. Eur J Pharmacol. 1990;182(3):587-589. [2]. Premakumar R, Sorger GJ, Gooden D. Repression of nitrate reductase in Neurospora studied by using L-methionine-DL-sulfoximine and glutamine auxotroph gln-1b. J Bacteriol. 1980;143(1):411-415. |