| Bioactivity | L-Hyoscyamine (Daturine), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine is a levo-isomer to Atropine (HY-B1205)[1][2]. | ||||||||||||
| In Vivo | L-Hyoscyamine (Daturine; 5-20 mg/kg; iv) prolongs the migrating MMC cycle length[1]. Animal Model: | ||||||||||||
| Name | L-Hyoscyamine | ||||||||||||
| CAS | 101-31-5 | ||||||||||||
| Formula | C17H23NO3 | ||||||||||||
| Molar Mass | 289.37 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lars Göran Axelsson, et al. Regulatory role of 5-HT and muscarinic receptor antagonists on the migrating myoelectric complex in rats. Eur J Pharmacol. 2003 Apr 25;467(1-3):211-8. [2]. Harald John, et al. Application of an enantioselective LC-ESI MS/MS procedure to determine R- and S-hyoscyamine following intravenous atropine administration in swine. Drug Test Anal. Mar-Apr 2012;4(3-4):194-8. |
L-Hyoscyamine
CAS: 101-31-5 F: C17H23NO3 W: 289.37
L-Hyoscyamine (Daturine), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagon
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