Bioactivity | L-Ent-oxPt IV is a oxaliplatin-based siderophore-platinum conjugate. L-Ent-oxPt IV exhibits selectivity towards Escherichia coli and antibacterial activity through DNA damage[1]. |
Invitro | L-Ent-oxPt IV (7.5-60 μM) 以表达 Ent 摄取机制的革兰氏阴性菌为靶点,在 K12 和 CFT073 菌株中启动裂解并诱导其丝状化[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> L-Ent-oxPt(IV) 相关抗体: |
Formula | C54H65N9O27Pt |
Molar Mass | 1467.22 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Guo C, et al., Investigation of Siderophore-Platinum(IV) Conjugates Reveals Differing Antibacterial Activity and DNA Damage Depending on the Platinum Cargo. ACS Infect Dis. 2024 Mar 4. |