| Bioactivity | L-651392 is an orally active and specific 5-lipoxygenase inhibitor that inhibits the production of leukotrienes. L-651392 controls the inflammatory process in Escherichia coli pyelonephritis by preventing inflammatory cells from reaching the site of infection and protecting the renal tubules from inflammation-related damage during pyelonephritis[1]. |
| CAS | 93211-49-5 |
| Formula | C14H10BrNO3S |
| Molar Mass | 352.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tardif M, et al. L-651,392, a potent leukotriene inhibitor, controls inflammatory process in Escherichia coli pyelonephritis[J]. Antimicrobial agents and chemotherapy, 1994, 38(7): 1555-1560. |