| Bioactivity | KwFwLL-NH2, a hexapeptide, is a ghrelin receptor ligand. KwFwLL-NH2 can act as a specific inverse agonist at the ghrelin receptor but with moderate potency (EC50=45.6 nM)[1]. |
| CAS | 942266-38-8 |
| Sequence | Lys-{D-Trp}-Phe-{D-Trp}-Leu-Leu-NH2 |
| Shortening | K-{D-Trp}-F-{D-Trp}-LL-NH2 |
| Formula | C49H66N10O6 |
| Molar Mass | 891.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Els S, et al. An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor. J Med Chem. 2012 Sep 13;55(17):7437-49. |
KwFwLL-NH2
CAS: 942266-38-8 F: C49H66N10O6 W: 891.11
KwFwLL-NH2, a hexapeptide, is a ghrelin receptor ligand. KwFwLL-NH2 can act as a specific inverse agonist at the ghrelin
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