Bioactivity | Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury[1][2]. |
Name | Kp7-6 |
CAS | 629628-53-1 |
Sequence | Tyr-Cys-Asp-Glu-His-Phe-Cys-Tyr (Disulfide bridge:Cys2-Cys7) |
Shortening | YCDEHFCY (Disulfide bridge:Cys2-Cys7) |
Formula | C48H56N10O15S2 |
Molar Mass | 1077.15 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhang S, et al. Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes. 2008 Feb;57(2):348-56. [2]. Hasegawa A, et al. Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6599-604. |