PeptideDB

Kp7-6

CAS: 629628-53-1 F: C48H56N10O15S2 W: 1077.15

Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects m
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Bioactivity Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury[1][2].
Name Kp7-6
CAS 629628-53-1
Sequence Tyr-Cys-Asp-Glu-His-Phe-Cys-Tyr (Disulfide bridge:Cys2-Cys7)
Shortening YCDEHFCY (Disulfide bridge:Cys2-Cys7)
Formula C48H56N10O15S2
Molar Mass 1077.15
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Zhang S, et al. Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes. 2008 Feb;57(2):348-56. [2]. Hasegawa A, et al. Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6599-604.