| Bioactivity | Ketorolac (RS37619) hemicalcium is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorola chemicalcium is also a DDX3 inhibitor that can be used for cancer research[1][4]. |
| Invitro | Ketorolac (RS37619) salt (0-30 μM; 48 h) effectively kills the oral cancer cells[4].Ketorolac salt (0-5 μM; 48 h) inhibits the expression of DDX3 protein, and induces apoptosis in H357 cells[4].Ketorolac salt (0-2.5 μM; 0-16 h) inhibits the proliferation of oral cancer cells[4].Ketorolac salt (0-50 μM) directly interacts with DDX3 and inhibits the ATPase activity[4]. Cell Viability Assay[4] Cell Line: |
| Name | Ketorolac hemicalcium |
| CAS | 167105-81-9 |
| Formula | C15H12CaNO3+ |
| Molar Mass | 274.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Ketorolac hemicalcium
CAS: 167105-81-9 F: C15H12CaNO3+ W: 274.31
Ketorolac (RS37619) hemicalcium is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibito
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This product is for research use only, not for human use. We do not sell to patients.