| Bioactivity | KWWCRW is a Holliday linker inhibitory peptide with anticancer activity. KWWCRW inhibits homologous recombination repair (HDR) during DNA repair by binding to the reactive Holliday linker intermediate and preventing its degradation, and inhibits site-specific recombination by bacteriophage in vitro[1]. |
| CAS | 292148-25-5 |
| Sequence | Lys-Trp-Trp-Cys-Arg-Trp |
| Shortening | KWWCRW |
| Formula | C48H61N13O7S |
| Molar Mass | 964.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qingbing Wang, et al. "Recent Advancements on Self‐Immolative System Based on Dynamic Covalent Bonds for Delivering Heterogeneous Payloads." Advanced healthcare materials 12.20 (2023): 2300138. |