Bioactivity | KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells[1]. | |||||||||
Target | IC50: 0.24 nM (ABHD6 in Neuro2A cells). | |||||||||
Name | KT182 | |||||||||
CAS | 1402612-62-7 | |||||||||
Formula | C27H26N4O2 | |||||||||
Molar Mass | 438.52 | |||||||||
Appearance | Solid | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9. |