| Bioactivity | KS124 (compound 3) is a potent ALDH inhibitor. KS124 shows inhibition for ALDH1A1, ALDH1A3, ALDH3A1. KS124 shows antiproliferative activity. KS124 induces apoptosis and ROS production[1]. |
| Invitro | KS124 (compound 3) (3 µM; 24, 48 h) 以时间依赖性方式诱导 HCT-116 细胞凋亡[1]。KS124 (3 µM; 48 h) 增加 HCT-116 细胞中的 ROS 生成[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> KS124 相关抗体: Cell Proliferation Assay[1] Cell Line: |
| Formula | C21H12Br2N2O7 |
| Molar Mass | 564.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gowda K, et al. Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor. Molecules. 2024 Jun 29;29(13):3114. |